Boswellia as an Option for Ulcerative Colitis or Crohn’s.
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Boswellia as an option for Ulcerative Colitis or Crohn’s Disease. Would Boswellia work for UC? Is Boswellia effective for Crohn’s Disease? Why Do I find Boswellia Irritating? And Why Would Boswellia Disrupt my Cycle?
These and many other questions I get from my clients.
Hi, I am Doctor Inna at Digestive Reset, and I am here weekly to answer your questions and give you my tips for digestive and hormone health, so your immune system gets in the great shape. And Please, always speak to your doctor while consuming our content.
Boswellia for Ulcerative Colitis and Crohn’s Disease? When it comes to UC:
We investigated Boswellia both the induction of remission as well as for maintenance of remission in patients with ulcerative colitis. Certain clinical research shows that taking Boswellia gum resin three times daily for 6 weeks increases the rate of remission when compared with taking sulfasalazine. Certain observational research shows that taking a lecithin-based delivery form of Boswellia extract for 4 weeks is associated with a reduction in symptoms and drug use in patients who are in remission.
Two clinical trials show that taking Boswellia gum resin can improve some symptoms and pathological measures of active ulcerative colitis. In one study, taking Boswellia gum resin 350 mg three times daily improved symptoms and disease markers in patients with ulcerative colitis. In this study, about 82% of patients taking Boswellia went into remission compared to 75% taking sulfasalazine. In another preliminary clinical study, taking Boswellia gum resin 300 mg three times daily for 6 weeks improved symptoms and some measures of disease pathology in about 90% of patients. In this study, 70% of patients taking Boswellia went into remission compared to 40% taking sulfasalazine 3 grams daily.
In patients with colitis in remission, one observational study has found that taking a specific lecithin-based delivery form of Boswellia extract (product called Casperome) 250 mg daily for 4 weeks is associated with a reduction in abdominal pain, cramps, and fatigue, a decrease in the need for additional medications, and a 58% lower risk for requiring additional medical care when compared with no treatment. Additionally, weekly episodes of bloody diarrhea, bowel movements, and watery stools were reduced when compared with baseline.
With Crohn’s Disease we found that there’s insufficient evidence.
Preliminary clinical research shows that taking Boswellia extract (H15) 1200 mg orally three times daily for 8 weeks reduces the severity of Crohn’s disease symptoms as effectively as mesalamine (brands like Asacol, Pentasa). However, the clinical impact of these results are questionable, because mesalamine is generally not considered to be an effective treatment for Crohn’s disease that is active or quiescent. Other clinical research shows that taking Boswellia (Boswelan) 800 mg orally three times daily does not increase rates of remissions and quality of life any more than placebo in patients with Crohn’s.Then why are many colitis patients find it ineffective and even irritating. Both Boswellia acids, especially AKBA, inhibit 5-lipoxygenase and reduce leukotriene synthesis and inhibit leukocyte elastase, which are the likely mechanisms for its anti-inflammatory and analgesic properties.
And here is where I’m going to make conclusions that are NOT on fact evidence based, but my practice and knowledge based. Full disclosure, these are my personal conclusions since I can’t find science backing this up yet. Think about taking Motrin or Advil, very effective for pain and inflammation. There are similarities in the mechanism of action. In theory, if it hurts your tummy when you take Motrin or Advil, you can also be irritated by Boswellia. And in theory, if you continuously take it and it disrupts your cycle, it is possible to connect it to gut microbiome disruption from the product used incorrectly or on empty stomach.
Also, in humans, Boswellia acids are poorly bioavailable from Boswellia; however, intake of fat may improve the absorption and bioavailability.
Announcement:
As of November 1st 2020, my practice is 100% remote. My physical office is officially closed due to my client’s demand and for their convenience. I am able to spend even more time with each of my clients so they get even more guidance throughout their healing journey. The sessions are on Zoom, the test kits come in the mail along with the supplements. If I’ll see the demand in the future, I’ll re-open a bigger and a better space for my amazing local clients. Thank you for being a part of my life and for being patient throughout these unprecedented times.If you’ve been thinking of scheduling a dive-in session with me, there’s never been a better time: CLICK HERE TO SCHEDULE.
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Sending LOVE,
Dr. Inna
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