Does the number on the scale never budge? OR worse…it only increases?

It can feel so frustrating when you feel like you’re doing everything right: your eating well and
you exercise consistently but your clothes don’t fit well and you feel like a failure for not being
able to lose the weight.

Weight loss resistance is MORE than a vanity problem. Excess weight is a risk factors for many
conditions such as:
● Heart disease (the number one cause of death in women world wide)
● Thyroid disorders
● Diabetes / insulin resistance
● Metabolic disease
● Chronic illness
● + more

If so, here are 6 common triggers to weight loss resistance that have NOTHING to do with diet
or exercise.

1. Environmental toxins

Environmental toxins are found all around us including these common household items:
● Candles
● Lotion
● Shampoo
● Makeup
● Food
● Water
These toxins mimic your hormones, such as estrogen, and can lead to an inability to lose
weight. In addition, if your body is unable to keep up with detoxing the amount of toxins it is
exposed to, it protects the essential organs by storing those excess toxins in fat.

2.Chronic stress

It’s all too common to reach for comfort food after a stressful day which can result in excessive
calorie intake.

Stress also impacts your hormones by causing your body to create cortisol, which is linked to
weight gain and an inability to lose body fat.

3.Hypothyroidism / underactive thyroid

Did you know up to 60% of Americans with hypothyroidism are unaware they have the problem.
Your thyroid is your master metabolic hormone and manages many of your body’s processes.
When it’s underperforming, metabolism slows, and weight gain increases.

4.Hormonal imbalances

Estrogen, progesterone, and testosterone also all play significant roles in stubborn weight.
All of these hormones can impact metabolism. Any imbalance in any of these hormones can
lead to a decrease in metabolic rate and an increase in fat storage. Testing to identify any
hormonal imbalances is key to create an individualized health plan.

5.Insulin resistance

Here’s how insulin resistance triggers a hormonal imbalance which can then lead to weight gain.
The individual eats a diet low in healthy fats and high in refined, processed carbohydrates such
as white bread, diet soda and pasta.

These foods cause a rapid rise in blood sugar to which the body manages with a compensatory
rise in insulin. This then causes a drastic decline in blood sugar for a short amount of time and
triggers a compensatory rise in cortisol levels.

The extra insulin travels with the new rise in blood sugar to transport the glucose into the cells
for storage or energy production. But over time the cells lose their ability to take in large
amounts of glucose and this state is called insulin resistance.

High levels of insulin can lead to an increase in production of testosterone in the ovaries in
addition to lower sex hormone binding globulin (SHBG) which can lead to an excess of estrogen
in the body. This excess estrogen can lead to excess fat storage, especially around the

6.Poor gut health

This means that your gut has a massive impact on your hormonal balance, and is often the root
of hormonal issues. Here are a few key hormones modulated by your gut microbiome:

● Your gut produces most of your serotonin. An inflamed gut can impair this production
and can lead to low levels of serotonin. Serotonin is best-known for increasing your
sense of happiness, but it also serves as a precursor for melatonin.

● Norepinephrine and epinephrine are also strongly linked to your gut health. These
hormones control your fight-or-flight response. Elevated levels, which can result from
harmful bacteria in your gut microbiome, cause stress, anxiety, and depression. This
triggers more hormonal issues in a vicious cycle.
● Estrogens are also regulated by the gut through the estrobolome.
● The gut and thyroid have a bidirectional relationship. Poor gut health can lead to thyroid
problems and thyroid disorders can contribute to leaky gut.

Which of these 6 hidden triggers surprised you?


Dr. Inna lukyanovsky, PharmD

Dr. Inna lukyanovsky, PharmD

Doctor of Pharmacy, Functional Medicine Practitioner, Gut Health Expert and Best Selling Author of the book "Crohn's and Colitis Fix."

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